Hepatitis C

Granulocyte colony stimulating factor for hepatitis C therapy associated neutropenia: systematic review and economic evaluation

Summary.  Hepatitis C virus (HCV) treatment requires maximal adherence to pegylated interferon (Pegâ€�IFN) and ribavirin to achieve a sustained virologic response (SVR). Neutropenia is the most common cause for Pegâ€�IFN... 
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Peginterferon with or without ribavirin has minimal effect on quality of life, behavioral/emotional, and cognitive outcomes in children

Conclusion:Overall QOL and psychosocial functioning are not deleteriously impacted by PEG 2a + RV or PL treatment of children with HCV. (HEPATOLOGY 2011.). (Source: Hepatology) Read More →
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Masking the 5′ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex [Biochemistry]

Hepatitis C virus subverts liver-specific microRNA, miR-122, to upregulate viral RNA abundance in both infected cultured cells and in the liver of infected chimpanzees. These findings have identified miR-122... 
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Serum visfatin is correlated with disease severity and metabolic syndrome in chronic hepatitis C infection

Conclusions:  Serum visfatin was correlated with disease severity and metabolic syndrome in CHC patients. (Source: Journal of Gastroenterology and Hepatology) Read More →
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